Επίκουρος Καθηγητής Ιατρικής Ογκολογίας, Πανεπιστήμιο της Χαϊδελβέργης

Πέτρος Χριστόπουλος

Petros Christopoulos is principal investigator in the Translational Lung Research Center Heidelberg and responsible for the scientific coordination of the Thoracic Oncology Program at Heidelberg University Hospital. He studied medicine in the University of Athens, Greece, and completed his training in internal medicine, emergency medicine, hematology, hematopoietic cell transplantation, medical oncology, genetic counseling, and palliative care in the University Hospitals of Freiburg and Würzburg in Germany.

A major focus of his research lies in the systematic integration of clinical with genetic, pathologic, immunologic and radiologic data to refine patient stratification and identify novel biomarkers and therapeutic targets. This approach was utilized in a pivotal work connecting the NCT, Pathology and DKFZ Heidelberg, to define and monitor molecular risk in ALK+ non-small-cell lung cancer (NSCLC), and is now expanded to other patient cohorts. A second main field is the characterization of systemic immune dysregulation associated with thoracic malignancies.

Multicolor flow cytometry, gene expression and TCR-profiling, proteomic and T-cell functional assays are combined to improve understanding of pathophysiology, immunotherapeutic efficacy and immune-related toxicities, while an important subproject explores thymoma-associated immunodeficiency. He is also responsible for the weekly thoracic molecular tumor board and subsequent treatment using novel compounds off-label or within expanded access programs.